P-418 Use of prophylactic and reactive feeding tubes in patients with esophageal cancer: A single-centre cohort study

Esophageal cancer (EC) patients suffer from significant cachexia prior to and during treatment with chemotherapy radiation (CRT). Feeding tubes can become the primary form of nutritional support for these after completion treatment. Our objective was identify factors that predict EC at high risk requiring feeding tube insertion. A retrospective cohort review completed. All an diagnosis made January 1, 2013 December 31, 2018 were included. Baseline characteristics all those receiving collected. multivariate logistic regression performed comparing group required a reactive insertion who did not require any factors. total 350 included in study, 132/350 (38%) received tube, gastrostomy being most common type inserted (72%). 82 out 132 (62%) had prophylactically, while 50/132 reactively. Amongst inserted, median age 67 years old, 74% male. Fifty-one (39%) adenocarcinoma, 75/132 (57%) squamous cell carcinoma, 5/132 (4%) neuroendocrine, 1/132 (1%) lymphoma. Severe dysphagia (OR 19.9, 95% CI 2.6-151.2, p < 0.001) decision undergo 2.8, 1.3-5.8, p=0.008) appeared be predictors Complications relating seen 24/50 (48%) 34/82 (41%) prophylactic (p=0.48). In this single-centre severe undergoing identified as later on. Future prospective studies further explore other may especially it appears have reactively more complications than prophylactically.